Begins in the lungs and ends in the lungs = Covid-19
COVID-19 (name of disease) is the same respiratory disease as influenza, and the new viral gene has many similarities with the SARS virus, so it was named SARS-CoV-2 (name of virus).
Specific symptoms may start with fever, cough, no smell or/and no taste, and eventually develop acute pneumonia like ARDS (Acute Respiratory Distress Syndrome) caused by Cytokine Storm.
The Lancet Medical Journal says that 25% of people are asymptomatic but others get infected from those infected people with no symptoms. 21% of the infected people become serious ill and need mechanical ventilation to survive from ARDS. The Lancet emphasizes that in the getting ill process of infected people there are clearly three steps:
- Viral Replication
- Cytokine Storm (Overreaction of Immune)
- Lung Collapse
The coronavirus itself does not mostly and directly damage the body but their own defense system of cytokines causes their body’s immune system to overreact, resulting in bad infections in own lungs, heart, kidneys, which may results in multiple organ failure such as sepsis.
- The sharpest divide came at age 70. Although 4% of patients in their 60s died, more than twice that, or 8.6%, of those in their 70s did, Covid-19 kills an estimated 14.8 % of patients 80 and older.
What is the cause of most dreadful symptom to make infected people fall into serious pneumonia?
IT IS CYTOKINE STORM causing Sudden Crash in Patients with COVID-19!!
TENS OF MILLIONS OF PEOPLE were killed by CYTOKINE STORM during the pandemic of Spanish flu.
Cytokine Storm is now understood as a major cause of mortality in the 1918-20 “Spanish flu”–which killed more than 50 million people worldwide and the H1N1 “swine flu” and H5N1 “bird flu” of recent years—and now COVID-19.
What Cytokines are causing infected people of Covid-19 with serial lung disease?
When the Cytokines that raise immune activity become too much abundant, the immune system is not able to stop itself (or Cytokine Storm). Those immune cells spread beyond infected body parts mainly from lungs and start attacking healthy tissues, gobbling up red and white blood cells and damaging the lung and liver. The blood vessels get so leaky that the lungs may fill with fluid and fall into acute respiratory distress.
Apart from a surge in main Cytokine of IL-6 (Interleukin-6), the body may also show high swirling levels of other Cytokines, Chemokines and Serine Protease called TNF (Tumor Necrosis Factor), IFN (Interferon)-α/β, IL-1(Interleukin-1), MCP1 (Monocyte Chemoattractant Protein)/CCL2 (C-C Motif Chemokine Ligand 2), neutrophil, monocyte-associated MMP (Matrix metallopoetidases)-9, and neutrophil elastase.
Do not Take it Easy
Some people don’t even get symptoms. Recent studies suggest as many as 80% or more of those infected are “Silent Carries”, showing no or very mild symptoms. It seems children and young, healthy people are more likely to be asymptomatic.
This is reason why we should stay home even if you feel completely fine.
No specific antiviral treatment drugs good for COVID-19 infection exists at present. .
Once the virus invaded into the human cells, unfortunately people infected with COVID-19 are treated with supportive care to help relieve symptoms such as steroids and other drugs but the efficacies of those drugs are questionable.
What should you do?
Boost Up an Excellent Adaptive Immune Response!!
Having a strong immune response during the incubation period can prevent the infection taking hold, reduce the actual quantity of virus in the body and prevent it from getting to the lungs.
By generating an early adaptive immune response, the body seems to recognize the virus during the incubation period and fight it off.
A person also needs to be generally healthy to be able to mount an appropriate immune response to the infection.
What drugs are used against the patients of Covid-19?
The below drugs have been used to treat the patients at many hospitals, ICU centers in the world. However, medical doctors find difficult to what treatments are best for the fast changing disease conditioned patients with what drugs to be used.
Approximately 65% of infected patients who took the above drugs suffered from side effect and more than 10% of the patients stopped using it due to the side effect.
Although pharmaceutical companies of the world race to find drugs that could help bring the pandemic under control, it may take a year to come up with a quality vaccine.
Blackcurrant Anthocyanins significantly inhibited H1N1 Virus attached to Human Cell!!
In 2002, Asahikawa Medical University announced that it had a remarkable inhibitory effect by 98% on the adsorption of influenza A and B on human cells by Anthocyanins/phenolic of blackcurrant.
Four species of influenza were blocked to enter into human cells by blackcurrant anthocyanins!!
In the year 2013, a joint research team led by Professor Suzutani of Fukushima Medical University and Asahikawa Medical University had disclosed studies done on the inhibition of virus adsorption that Kurokarin (blackcurrant) had a remarkable inhibitory effect of 98% inhibition on the adsorption of pandemic influenza A (H1N1) 2009, Hong Kong influenza (IFV-AH3), and Russian influenza (IFV-AH1).
Not only for Influenza Viruses, blackcurrant anthocyanins has remarkable anti virus power
Blackcurrant Anthocyanins are effectively inhibited a highly contagious infection of Herpes and Adenovirus infection!!
In addition, blackcurrant anthocyanins inhibited on the cell membrane the herpes bacillus (HSV-1) and pharyngitis infecting the mouth, throat and eye areas cause swelling, throat pain and high fever.
Many studies show that Blackcurrant anthocyanins and polyphenols suppress the replication of adenovirus infectious bacteria (AdV = pool fever) that causes conjunctivitis that causes irritation of the eye, tonsillitis, and eye congestion.
Remarkable Power to Boost Your Immune System by Blackcurrant Anthocyanins
Cytokines and Serine Proteinases causing inflammation are significantly reduced!!
Studies done at Pennsylvania University showed that the blackcurrant extract inhibited all serine proteinases, MMP-1 and MMP-9, inflammatory compounds of Cytokine Storm, were significantly inhibited by blackcurrant anthocyanins during 4 hours incubation test. Serine proteinases related periodontal diseases were also significantly inhibited by blackcurrant anthocyanins.
Most Effective Adaptive Immune Response by Blackcurrant Anthocyanins
Numerous studies shows that blackcurrant anthocyanins (BA) dampen inflammation through multiple pathways. Directly or indirectly the four compositions of blackcurrant anthocyanins and polyphenols suppress the activity of nuclear transcription factors, such as NFκB, and reduce the production of pro-inflammatory enzymes and cytokines, including COX2, tumor necrosis factor (TNF)-α, and interleukin (IL)-4, 6, 8 with serine proteases while anti-inflammatory cytokines IL10 , IL13 secreted by BA support to counterbalance the adaptive immune cells in inflammatory diseases.
Please Stay Safe and Healthy For Yourself and Your Family!!
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Please be advised that we haven’t tested blackcurrant anthocyanins on the cell adsorption and/or Cytokine Storm in vitro or by human. However, Blackcurrant anthocyanins contained in Blackcurrant Extract Powder support to improve our immune system by taking it for a while from many studies done in the past 20 years.